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1

Comparison of Treatment of Severe High-Density Lipoprotein Cholesterol Deficiency in Men With Daily Atorvastatin (20 mg) Versus Fenofibrate (200 mg) Versus Extended-Release Niacin (2 g)

Khalid Alrasadi, Zuhier Awan, Khalid Alwaili, Isabelle Ruel, Anouar Hafiane, Larbi Krimbou, Jacques Genest

Journal:

The American Journal of Cardiology

Year:

2008

Language:

english

File:

PDF, 790 KB

english, 2008

2

The HDL proteome in acute coronary syndromes shifts to an inflammatory profile

Khalid Alwaili, Dana Bailey, Zuhier Awan, Swneke D. Bailey, Isabelle Ruel, Anouar Hafiane, Larbi Krimbou, Sylvie Laboissiere, Jacques Genest

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2012

Language:

english

File:

PDF, 755 KB

english, 2012

3

Molecular and Cellular Physiology of Apolipoprotein A-I Lipidation by the ATP-binding Cassette Transporter A1 (ABCA1)

Denis, M., Haidar, B., Marcil, M., Bouvier, M., Krimbou, L., Genest, J.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 483 KB

english, 2004

4

Compound heterozygosity at the sphingomyelin phosphodiesterase-1 (SMPD1) gene is associated with low HDL cholesterol

Ching Yin Lee,Larbi Krimbou,Jérôme Vincent,Chantal Bernard…

Journal:

Year:

2003

Language:

english

File:

PDF, 259 KB

english, 2003

5

High-density lipoproteins: multifunctional vanguards of the cardiovascular system

Marcil, Michel, O'Connell, Brian, Krimbou, Larbi, Genest Jr, Jacques

Journal:

Expert Review of Cardiovascular Therapy

Year:

2004

Language:

english

File:

PDF, 1.21 MB

english, 2004

6

Cellular cholesterol homeostasis in vascular endothelial cells

Houssein Hajj Hassan, Maxime Denis, Larbi Krimbou, Michel Marcil, Jacques Genest

Journal:

Canadian Journal of Cardiology

Year:

2006

File:

PDF, 275 KB

2006

7

Expression, regulation, and activity of ABCA1 in human cell lines

Maxime Denis, Rachel Bissonnette, Bassam Haidar, Larbi Krimbou, Michel Bouvier, Jacques Genest

Journal:

Molecular Genetics and Metabolism

Year:

2003

Language:

english

File:

PDF, 272 KB

english, 2003

8

A novel nonsense apolipoprotein A-I mutation (apoA-IE136X) causes low HDL cholesterol in French Canadians

Zari Dastani, Carole Dangoisse, Betsie Boucher, Katia Desbiens, Larbi Krimbou, Robert Dufour, Robert A. Hegele, Päivi Pajukanta, James C. Engert, Jacques Genest, Michel Marcil

Journal:

Atherosclerosis

Year:

2006

Language:

english

File:

PDF, 314 KB

english, 2006

9

Abstract: 1453 RVX-208 A SMALL MOLECULE INCREASES APOA-I, PREB-HDL, AND FUNCTIONALITY OF HDL IN HUMANS

Gordon, A, Jahagirdar, R, Johansson, J, Chiacchia, F, Hansen, H, Wagner, G, Bailey, D, Krimbou, L, Genest, J, Wong, N

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 111 KB

english, 2009

10

RVX-208: A Small Molecule That Increases Apolipoprotein A-I and High-Density Lipoprotein Cholesterol In Vitro and In Vivo

Dana Bailey, Ravi Jahagirdar, Allan Gordon, Anouar Hafiane, Steven Campbell, Safia Chatur, Gregory S. Wagner, Henrik C. Hansen, Fabrizio S. Chiacchia, Jan Johansson, Larbi Krimbou, Norman C.W. Wong, J

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 1.27 MB

english, 2010

11

Gamma-LpE (γ-LpE) concentrations was regulated by cell membranes and phospholipids

Larbi Krimbou, Michel Marcil, Nancy Doyle, Jacques Genest Jr, Jean Davignon

Journal:

Atherosclerosis

Year:

2000

Language:

english

File:

PDF, 355 KB

english, 2000

12

2.P.5 In vitro factors affecting the concentration of gamma-LpE (γ-LpE) in human plasma

L. Krimbou, M. Tremblay, H. Jacques, J. Davignon, J.S. Cohn

Journal:

Atherosclerosis

Year:

1997

Language:

english

File:

PDF, 356 KB

english, 1997

13

Plasma remnant-like particle lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects

Caroline Marcoux, Michel Tremblay, Alexandre Fredenrich, Hélène Jacques, Larbi Krimbou, Katsuyuki Nakajima, Jean Davignon, Jeffrey S Cohn

Journal:

Atherosclerosis

Year:

1998

Language:

english

File:

PDF, 138 KB

english, 1998

14

4.P.338 Familial HDL deficiency: A cellular cholesterol transport defect

Genest, J., Marcil, M., Yu, L., Batal, R., Krimbou, L., Boucher, B., Davignon, J., Oram, J.F., Cohn, J.S.

Journal:

Atherosclerosis

Year:

1997

Language:

english

File:

PDF, 164 KB

english, 1997

15

Abnormal HDL3 and apo Al-mediated cellular cholesterol efflux in subjects with familial HDL deficiency

Marcil, Michel, Krimbou, Larbi, Boucher, Betsie, Solymoss, B.C., Cohn, Jeffrey S., Genest, Jacques

Journal:

Journal of the American College of Cardiology

Year:

1996

Language:

english

File:

PDF, 155 KB

english, 1996

16

Carboxyl-Terminal Disulfide Bond of Acid Sphingomyelinase Is Critical for Its Secretion and Enzymatic Function †

Lee, Ching Yin, Tamura, Taku, Rabah, Nadia, Lee, Dong-Young Donna, Ruel, Isabelle, Hafiane, Anouar, Iatan, Iulia, Nyholt, Dana, Laporte, Frédéric, Lazure, Claude, Wada, Ikuo, Krimbou, Larbi, Genest, J

Journal:

Year:

2007

Language:

english

File:

PDF, 558 KB

english, 2007

17

Characterization of Oligomeric Human ATP Binding Cassette Transporter A1: POTENTIAL IMPLICATIONS FOR DETERMINING THE STRUCTURE OF NASCENT HIGH DENSITY LIPOPROTEIN PARTICLES

Denis, M., Haidar, B., Marcil, M., Bouvier, M., Krimbou, L., Genest, J.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 749 KB

english, 2004

18

Apolipoprotein A-I Activates Cellular cAMP Signaling through the ABCA1 Transporter

Haidar, B., Denis, M., Marcil, M., Krimbou, L., Genest, J.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 734 KB

english, 2004

19

Quantitative Analysis of ABCA1-dependent Compartmentalization and Trafficking of Apolipoprotein A-I: IMPLICATIONS FOR DETERMINING CELLULAR KINETICS OF NASCENT HIGH DENSITY LIPOPROTEIN BIOGENESIS

Hassan, H. H., Bailey, D., Lee, D.-Y. D., Iatan, I., Hafiane, A., Ruel, I., Krimbou, L., Genest, J.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 495 KB

english, 2008

20

Interaction of Lecithin:Cholesterol Acyltransferase (LCAT){middle dot} 2-Macroglobulin Complex with Low Density Lipoprotein Receptor-related Protein (LRP): EVIDENCE FOR AN 2-MACROGLOBULIN/LRP RECEPTOR-MEDIATED SYSTEM PARTICIPATING IN LCAT CLEARANCE

Krimbou, L., Marcil, M., Davignon, J., Genest, J.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 821 KB

english, 2001

21

Structural and functional properties of human plasma high density-sized lipoprotein containing only apoE particles

Journal:

The Journal of Lipid Research

Year:

2003

Language:

english

File:

PDF, 5.86 MB

english, 2003

22

Biogenesis and speciation of nascent apoA-I-containing particles in various cell lines

Journal:

The Journal of Lipid Research

Year:

2005

Language:

english

File:

PDF, 446 KB

english, 2005

23

Familial HDL Deficiency Characterized by Hypercatabolism of Mature ApoA-I but Not ProApoA-I

Batal, R., Tremblay, M., Krimbou, L., Mamer, O., Davignon, J., Genest, J., Cohn, J. S.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

1998

Language:

english

File:

PDF, 1.67 MB

english, 1998

24

Identification of an ABCA1-dependent phospholipid-rich plasma membrane apolipoprotein A-I binding site for nascent HDL formation: implications for current models of HDL biogenesis

Hassan, H. H., Denis, M., Lee, D.-Y. D., Iatan, I., Nyholt, D., Ruel, I., Krimbou, L., Genest, J.

Journal:

The Journal of Lipid Research

Year:

2007

Language:

english

File:

PDF, 557 KB

english, 2007

25

Membrane microdomains modulate oligomeric ABCA1 function: impact on apoAI-mediated lipid removal and phosphatidylcholine biosynthesis

Iatan, I., Bailey, D., Ruel, I., Hafiane, A., Campbell, S., Krimbou, L., Genest, J.

Journal:

The Journal of Lipid Research

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

26

Cellular Cholesterol Transport and Efflux in Fibroblasts Are Abnormal in Subjects With Familial HDL Deficiency

Marcil, M., Yu, L., Krimbou, L., Boucher, B., Oram, J. F., Cohn, J. S., Genest, J.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

1999

Language:

english

File:

PDF, 744 KB

english, 1999

27

Molecular interactions between apoE and ABCA1: impact on apoE lipidation

Journal:

The Journal of Lipid Research

Year:

2004

Language:

english

File:

PDF, 4.35 MB

english, 2004

28

Analysis of lipid transfer activity between model nascent HDL particles and plasma lipoproteins: implications for current concepts of nascent HDL maturation and genesis

Bailey, D., Ruel, I., Hafiane, A., Cochrane, H., Iatan, I., Jauhiainen, M., Ehnholm, C., Krimbou, L., Genest, J.

Journal:

The Journal of Lipid Research

Year:

2010

Language:

english

File:

PDF, 1.57 MB

english, 2010

29

Disorders of high‐density lipoprotein biogenesis

Krimbou, Larbi, Ruel, Isabelle, Dastani, Zari, Alrasadi, Khalid, Hajj Hassan, Houssein, Iatan, Iulia, Marcil, Michel, Genest, Jacques

Journal:

Annals of Medicine

Year:

2008

Language:

english

File:

PDF, 470 KB

english, 2008

30

RVX 208: a small molecule that raises HDL

Genest, Jacques, Krimbou, Larbi, Wong, Norman

Journal:

Clinical Lipidology

Year:

2010

Language:

english

File:

PDF, 587 KB

english, 2010

31

New insights into the biogenesis of human high-density lipoproteins

Krimbou, Larbi, Marcil, Michel, Genest, Jacques

Journal:

Current Opinion in Lipidology

Year:

2006

Language:

english

File:

PDF, 1.35 MB

english, 2006